Granalix is planning a clinical trial for early AD patients.
Granalix is planning a clinical trial for MS patients in which GranaGard will be administered in addition to conventional drugs.
Granalix is planning a clinical trial for CJD patients and carriers of CJD related mutations.
Preliminary experiments have shown that GranaGard can modulate the activity of mitochondrial enzymes, resulting in reduction of reactive species production thereby reducing the toxicity of respiration to cells.
Treatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and is associated with demyelination, neurodegeneration, and sensitivity to oxidative stress. In this work, we administered a nanodroplet formulation of pomegranate seed oil (PSO), denominated Nano-PSO, to mice induced for experimental autoimmune encephalomyelitis (EAE), an established...
Granalix is conducting a survey among people taking GranaGard for several months. No adverse effect have been reported. Among the benefits most described were: Increased alertness and fitness for physical activity.
Preliminary experiments have shown that GranaGard can reduce the activity of Complex I in the respiratory chain of the mitochondria. While this can somewhat reduce the production of ATP, it can concomitantly inhibit the formation of free radicals, thereby reducing the toxicity of respiration to cells.
Pomegranate seed oil nanoemulsions for the prevention and treatment ofneurodegenerative diseases: the case of genetic CJD
Neurodegenerative diseases generate the accumulation of specific misfolded proteins, such as PrPSc prions or A-beta in Alzheimer’s diseases, and share common pathological features, like neuronal death and oxidative damage. To test whether reduced oxidation alters disease manifestation, we treated TgMHu2ME199K mice, modeling for genetic prion disease, with Nano-PSO, a...
GranaGard is a sub-micron pomegranate seed oil formulation, For the delivery of naturalneuroprotection to the brain