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GranaGard Nano-Omega 5 Scientific Studies

About the research

Granalix aims to provide its customers with products based on science and natural ingredients. The company’s labs are run by Prof. Ruth Gabizon from Hadassah Medical Center and Prof. Shlomo Magdassi from the Hebrew University. The company’s laboratories conduct research on various models to assess the safety and effects of the company’s products. These studies have been published in leading scientific journals following thorough peer review.

Relevant studies on the company’s products are also implemented in clinical trials with humans, in close collaboration with the neurology departments at Hadassah Hospital and Ichilov Hospital, as well as the neuropsychology department at Rambam Hospital and a research institute in Mexico.

2023

Latest studies

12% improvement in cognitive abilities.

The trial in humans was conducted at Hadassah Ein Kerem University Hospital in Jerusalem, by Prof. Dimitrius Karussis, an international renowned neurologist, along with Dr. Panayiota Petrou. The trial was approved by the Helsinki Committee for Clinical Trials in Humans.

It was found that in people who received GranaGard for just 3 months, exhibited a 12% improvement in the CVLT-II test which measures cognitive memory abilities.

GranaGard and Anti-aging

Comparing the anti-aging hallmark activities of Nano-PSO in a mouse model of genetic Creutzfeldt-Jakob Disease

GranaGard and recovery from head injuries

Nano-PSO Administration Attenuates Cognitive and Neuronal Deficits Resulting from Traumatic Brain Injury

All studies

September 2021

12% improvement in cognitive abilities

Beneficial effects of a nano formulation of pomegranate seed oil, GranaGard, on the cognitive function of multiple sclerosis patients

P. Petrou MD, A. Ginzberg PhD., O. Binyamin PhD. and D. Karussis MD, PhD.

  • Clinical trials in humans
  • Pomegranate seed oil
  • Nano-Omega-5

April 2022

GranaGard and recovery from head trauma

Nano-PSO Administration Attenuates Cognitive and Neuronal Deficits Resulting from Traumatic Brain Injury

D Qubty, K Frid, M Har-Even, V Rubovitch, R Gabizon

  • Tested in laboratory animals
  • Pomegranate seed oil
  • Nano-Omega-5

February 2022

GranaGard and anti-aging

Comparing anti–aging hallmark activities of Metformin and Nano-PSO in a mouse model of genetic Creutzfeldt-Jakob Disease

O Binyamin, K Frid, G Keller, A Saada, R Gabizon

  • Tested in laboratory animals
  • Pomegranate seed oil
  • Nano-Omega-5

September 2020

Accelerated breakdown of fatty acids in the liver

Punica granatum L.-derived omega-5 nanoemulsion improves hepatic steatosis in mice fed a high fat diet by increasing fatty acid utilization in hepatocytes

K. Zamora-López, L. G. Noriega, A. Estanes-Hernández, I. Escalona-Nández, S. Tobón-Cornejo, A. R. Tovar, V. Barbero-Becerra & C. Pérez-Monter

  • Tested in laboratory animals
  • Pomegranate seed oil
  • Nano-Omega-5

December 2019

GranaGard affects cognition

Brain targeting of 9c,11t-Conjugated Linoleic Acid, a natural calpain inhibitor, preserves memory and reduces Aβ and P25 accumulation in 5XFAD mice

O Binyamin, K Nitzan, K Frid, Y Ungar, H Rosenmann, R Gabizon

  • Tested in laboratory animals
  • Pomegranate Seed Oil
  • Nano-Omega 5

April 2019

GranaGard and free radicals

Mitochondrial dysfunction in preclinical genetic prion disease: A target for
preventive treatment?

G Keller, O Binyamin, K Frid, A Saada, R Gabizon

  • Tested in laboratory animals
  • Pomegranate Seed Oil
  • Nano-Omega 5

August 2017

GranaGard and life span

Continues administration of Nano-PSO significantly increased survival of genetic CJD mice

Binyamin O, Keller G, Frid K, Larush L, Magdassi S, Gabizon R.

  • Tested in laboratory animals
  • Pomegranate Seed Oil
  • Nano-Omega 5

November 2015

GranaGard and anti-inflammatory activity

Treatment of a multiple sclerosis animal model by a novel nanodrop formulation of a natural antioxidant

Binyamin O, Larush L, Frid K, Keller G, Friedman-Levi Y, Ovadia H, Abramsky O, Magdassi S, Gabizon R

  • Tested in laboratory animals
  • Pomegranate Seed Oil
  • Nano-Omega 5
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